2020届二轮复习阅读理解热点话题专题之二十三：瑞德西韦在武汉的临床试验中具有治疗病毒的潜力 11页

‎2020届二轮复习阅读理解热点话题专题之二十三：瑞德西韦在武汉的临床试验中具有治疗病毒的潜力 Drug Remdesivir with potential to treat virus in clinical trials in Wuhan 瑞德西韦在武汉的临床试验中具有治疗病毒的潜力 读前导读：‎ 周三，美国生物技术公司吉利德在研药物瑞德西韦在新型冠状病毒爆发的湖北省武汉市开始进行临床试验。专家们希望瑞德西韦以及其他已经在动物试验中被证明对病毒有效的药物，也能有效治疗实际感染病毒的患者。‎ Part1：高级实词分类记 名词 1. trial试验 2. potency /ˈpəʊtnsi/效力 3. case案例 4. infection感染 5. ceremony仪式 6. nucleotide /'njuːklɪətaɪd/核苷酸 7. analog /'ænəlɒɡ/模拟的；模拟物 adj/n 8. effectiveness有效性 9. coronavirus冠状病毒 形容词 1. clinical ‎ 2. effective ‎ 3. mild ‎ 4. moderate /ˈmɒdərət /‎ Even moderate amounts of the drug can be fatal. ‎ The team enjoyed only moderate success last season. ‎ Cook over a moderate heat. 。 ‎ moderate views/policies  ‎ 5. investigational /ɪnˌvestɪˈɡeɪʃnəl// ‎ 6. broad-spectrum /ˈspektrəm/ ‎ 7. antiviral ‎ 8. novel ‎ 9. vitro /ˈviːtrəʊ/ adj. ‎ 动词 1. approve___________________‎ 2. assess___________________‎ 3. launch /lɔːntʃ/ ___________________‎ ‎1）to launch an appeal/an inquiry/an investigation/a campaign ‎ to launch an attack/invasion _________________________‎ ‎2）（首次）上市，发行 ‎ 新型号产品将在七月推出。‎ ‎ ________________________________________________‎ ‎3）使（船，尤指新船）下水 海军今天有一艘新军舰要下水。‎ ‎______________________________________________‎ 1. demonstrate /ˈdemənstreɪt/  vt. _______________________‎ 其他词类 1. globally.‎ 2. structurally Part2：高级词汇拓展 1. effectiveness有效性 adj _________________ adv ____________‎ 2. clinical临床 adv____________ n ____________‎ 3. mild温和的 adv ____________ n ____________‎ 4. moderate /ˈmɒdərət适度的；中等的；温和的；不激烈的；不偏激的 5. investigational /ɪnˌvestɪˈɡeɪʃnəl//调查的 n ____________ ‎ vt ____________ n 调查者____________‎ 6. approve批准 n ____________‎ 7. assess评估 n ____________‎ 8. demonstrate /ˈdemənstreɪt/  vt. 证明；展示；论证vi. 示威 n: 证明；展示；论___________________‎ ‎ adj /dɪˈmɒnstrətɪv/____________‎ ‎ adj. 说明的；证明的；公开表露感情的 ____________‎ ‎ /ˈdemənstreɪtə(r)/ n. 示威者；论证者；指示者；证明者____________‎ Part3：高级短语荟萃 1. clinical trials ‎ 2. along with others ‎ 3. be effective against the virus ‎ 4. work well in ‎ 5. be approved by ‎ 6. China's National Medical Products Administration 7. be conducted by 8. the China-Japan Friendship Hospital 9. the Chinese Academy of Medical Sciences ‎ 10. a total of ‎ 11. in two trials ‎ 12. assess the drug's potency 13. with mild or moderate infections 14. severely infected patients 15. in a launch ceremony ‎ 16. structurally similar to ‎ Part4：原汁文章思维能力提升训练 ‎ Clinical trials of the United States biotech company Gilead Sciences' experimental drug Remdesivir have begun on Wednesday in Wuhan, Hubei province, the center of the novel coronavirus outbreak.‎ Experts hope this drug, along with others that have shown to be effective against the virus in animal tests, can also work well in actual human patients.‎ The Phase III trials have been approved by China's National Medical Products Administration and will be conducted by the China-Japan Friendship Hospital and the Chinese Academy of Medical Sciences on patients at the Wuhan Jinyintan Hospital.‎ The project will study a total of 761 patients in two trials -- one trial is to assess the drug's potency on 308 cases with mild or moderate infections, and the other is on 453 severely infected patients, Cao Bin, the head of the clinical trial and vice-president of the friendship hospital, said in a launch ceremony on Wednesday.‎ Remdesivir is an investigational nucleotide analog with broad-spectrum antiviral activity that has not been approved anywhere globally.‎ It has demonstrated effectiveness in vitro and in animal models against viral pathogens MERS and SARS, which are also coronaviruses and are structurally similar to the novel coronavirus from Wuhan.‎ ‎ 2020-02-07‎ ‎1. Why is Remdesivir approved to treat the patients infected with coronaviruses?‎ ‎2. What trials will be done before Remdesivir is used in medical treatment?‎ 判断 Remdesivir has been approved to treat antivirus-related diseases globally.‎ Part5：报刊复杂句式剖析。‎ ‎1.Experts hope this drug, along with others that have shown to be effective against the virus in animal tests, can also work well in actual human patients.‎ 翻译：____________________________________________________________‎ ‎___________________________________________________________________ ‎ 解析: 本句的主干Experts hope_____________________________________.为主从复合句。从句是一个宾语从句。枝叶部分：along with others that have shown to be effective against the virus in animal tests为介词短语做_____________语。其中划线部分为______________从句修饰others:其他的药物。‎ ‎2.The project will study a total of 761 patients in two trials -- one trial is to assess the drug's potency on 308 cases with mild or moderate infections, and the other is on 453 severely infected patients, Cao Bin, the head of the clinical trial and vice-president of the friendship hospital, said in a launch ceremony on Wednesday.‎ 翻译： __________________________________________________________ ‎ ‎_____________________________________________________________________‎ ‎_____________________________________________________________________‎ 解析: 本句的主干：__________________________________, Cao Bin, said.‎ 为主谓宾结构。‎ 其中破折后解释two trials的内容。-- one trial is to assess …., and the other is …..主句部分：Cao Bin, the head of the clinical trial and vice-president of the friendship hospital, said in a launch ceremony on Wednesday.主语有一个______________: the head of the clinical trial and vice-president of the friendship hospital修饰Cao Bin.句子看似很长，结构还是比较清晰的。‎ 相关话题语法填空 A ‎ Dr. Li Wenliang, one of the eight “whistleblowers” who tried _____1_____ (warn) fellow medics of the novel coronavirus when it first emerged in Wuhan, died early on Friday. Wuhan Central Hospital _____2_____ (confirm) in a statement released on _____3_____ (it) official Weibo account. “Our hospital’s ophthalmologist Li Wenliang was _____4_____ (unfortunate) infected with coronavirus during his work in the fight _____5_____ the coronavirus epidemic,” the statement read, ____6_____ (add) “He died at 2:58 a.m. on February 7 after attempts to resuscitate were unsuccessful.” ‎ ‎ “After emergency treatment, Li Wenliang passed away,” the Central Hospital of Wuhan announced on Weibo, China’s version of Twitter. “We 7._____________(deep) regret and mourn Li’s death.”‎ ‎ Dr. Li is a hero, _____8_____ will live in our hearts forever. May God bless all the courageous doctors and nurses fighting on the front line.‎ ‎1.____________2. ____________3. ___________4._____________‎ ‎5. ____________6. ____________7. ____________8. ____________‎ ‎ ‎ B Drones have stepped forward as efficient tools in 1.___________ (promote) knowledge about preventing infection and taking up tasks including checking body temperatures and spraying disinfectant amid the novel coronavirus epidemic in China.‎ A picture2. ___________(take) by Xinhua News Agency showed an operator using his drone to check the temperatures of residents in a community in Yichun, Jiangxi province, on Jan 29. ‎ The drone, 3. ___________(equip) with an infrared thermal imaging lens and a loudspeaker, can detect people with fever at a certain distance and broadcast messages about 4. ___________ (protect) measures to residents, a Xinhua report said.‎ That way, the spread of the virus could 5. ___________（prevent）, it said, since people did not need to be in close contact.‎ In other places, drones are being used to patrol villages and urban roads to check for any behavior 6_______that might contribute to the spread of the virus, such as people not ____7_______(wear) masks in public.‎ ‎1.____________2. ____________3. ___________4._____________‎ ‎5. ____________6. ____________7. ____________‎ 双语阅读 Clinical trials of the United States biotech company Gilead Sciences' experimental drug Remdesivir have begun on Wednesday in Wuhan, Hubei province, the center of the novel coronavirus outbreak.‎ 周三，美国生物技术公司吉利德在研药物瑞德西韦在新型冠状病毒爆发的湖北省武汉市开始进行临床试验。‎ Experts hope this drug, along with others that have shown to be effective against the virus in animal tests, can also work well in actual human patients.‎ 专家们希望瑞德西韦以及其他已经在动物试验中被证明对病毒有效的药物，也能有效治疗实际感染病毒的患者。‎ The Phase III trials have been approved by China's National Medical Products Administration and will be conducted by the China-Japan Friendship Hospital and the ‎ Chinese Academy of Medical Sciences on patients at the Wuhan Jinyintan Hospital.‎ 瑞德西韦三期临床试验已获国家药品监督管理局批准，由中日友好医院和中国医学科学院在武汉金银滩医院开展。‎ The project will study a total of 761 patients in two trials -- one trial is to assess the drug's potency on 308 cases with mild or moderate infections, and the other is on 453 severely infected patients, Cao Bin, the head of the clinical trial and vice-president of the friendship hospital, said in a launch ceremony on Wednesday.‎ 周三，瑞德西韦临床试验项目负责人、中日友好医院副院长曹彬教授在项目启动会上介绍，瑞德西韦临床试验拟入组761例患者，采用两组试验对照方法评估药物的效力，其中一组为308例轻、中症患者，另一组为453例重症患者。‎ Remdesivir is an investigational nucleotide analog with broad-spectrum antiviral activity that has not been approved anywhere globally.‎ 瑞德西韦是一种具有广谱抗病毒活性的核苷类药物，目前还没有在全球任何国家得到批准。‎ It has demonstrated effectiveness in vitro and in animal models against viral pathogens MERS and SARS, which are also coronaviruses and are structurally similar to the novel coronavirus from Wuhan.‎ 它已经在体外和动物试验中证明了对病毒病原体MERS和SARS的有效性，它们也属于冠状病毒，在结构上类似于武汉的新型冠状病毒。‎ ‎ ‎ 语法填空双语阅读 Drones have stepped forward as efficient tools in promoting knowledge about preventing infection and taking up tasks including checking body temperatures and spraying disinfectant amid the novel coronavirus epidemic in China.‎ 在中国出现新型冠状病毒流行的情况下，无人机已经成为传播预防感染知识的有效工具，并承担了检查体温和喷洒消毒剂等任务。‎ A picture taken by Xinhua News Agency showed an operator using his drone to check the temperatures of residents in a community in Yichun, Jiangxi province, on Jan 29.‎ ‎1月29日，新华社拍摄的一张照片显示，在江西省宜春市的一个社区，一名操作员正在用无人机测量居民的体温。‎ The drone, equipped with an infrared thermal imaging lens and a loudspeaker, can detect people with fever at a certain distance and broadcast messages about protective measures to residents, a Xinhua report said.‎ 据新华社报道，该无人机配有红外热成像镜头和扬声器，可以在一定距离内探测到发烧的人，并向居民广播有关保护措施的信息。‎ That way, the spread of the virus could be thwarted, it said, since people did not need to be in close contact.‎ 这样就可以阻止病毒的传播，因为人们不需要密切接触。‎ In other places, drones are being used to patrol villages and urban roads to check for any behavior that might contribute to the spread of the virus, such as people not wearing masks in public.‎ 在其他地方，无人机被用来巡逻村庄和城市道路，检查任何可能导致病毒传播的行为，比如人们在公共场合不戴口罩。‎ ‎1. /drəʊn/ [ usually sing. ] a continuous low noise 嗡嗡声;无人机 ‎2. thwart v. /θwɔːt/ to prevent sb from doing what they want to do 阻止；阻挠；对…构成阻力 ‎• to thwart sb's plans 阻挠某人的计划 ‎• She was thwarted in her attempt to take control of the party. 她控制这个政党的企图受阻了。‎